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Mature skin: Say no to general loss of volume

Img_Mature skin: Say no to general loss of volume

You want denser, plump skin that feels full to the touch? To specifically fight general loss of volume, La Roche-Posay has broken new ground with SUBSTIANE [+] Serum, the first fundamental volume anti-aging concentrate.

The symptoms

General loss of volume is characteristic of mature skin

Dryness, pigmentation marks, redness, uneven skin tone, wrinkles... we are all familiar with the signs that mark mature skin. But there is another one, less talked about, despite being a major concern for women: the general loss of volume that occurs at two levels:

  • In depth, the fundamental substance diminishes, skin loses its density and collapses.
  • On the surface, the skin becomes thinner and more fragile. Women can feel that their skin is less plump, that it has lost its density.

As a result, skin becomes less elastic and less toned. Wrinkles and furrows form, cheeks are less chubby, facial contours lose their clarity, and features are less harmonious.

In figures


LR2412 is a new anti-aging molecule, the result of 10 years of research and protected by 26 patents. Inspired by the defense mechanisms of plants and derived from jasmonic acid, it was selected by the Roche-Posay laboratories for its remarkable effectiveness, its incredible bioavailability, and its excellent tolerability.

The La Roche-Posay solution

The unique combination of two ultra-talented anti-aging active ingredients

As time passes, the dermis loses its density deep down and the skin becomes slacker. After a certain age, it also loses its surface volume, it becomes thinner and more fragile. Women can feel that their skin is less firm to the touch, and want visible results. Aware of this need, the La Roche-Posay laboratories have developed SUBSTIANE [+] Serum, an exclusive combination of two ultra-talented anti-aging active ingredients:

1. Pro-Xylane recreates skin density
Its action helps restore skin density, correct sagging features, and restructure the face.

2. LR2412 reinforces and complements the action of Pro-Xylane
It takes over from the action of Pro-Xylane to act all the way through to the surface and restore the skin's bounce.

In figures


2 ultra-talented active ingredients-LR2412 + PRO-XYLANE™-at ideal doses for a unique complementary combination that fundamentally restores skin volume. At the concentrations calculated by La Roche-Posay, both molecules have clinically demonstrated the full extent of their effectiveness.

In practice

A dab of serum is all you need to give your beauty routine a boost

Highly concentrated in active ingredients and designed specifically to penetrate instantly deep into the skin, the serum is an ideal ally for an optimal beauty routine. Because its texture is both rich and comfortable, SUBSTIANE [+] Serum can be used alone or in addition to your usual cream, depending on your skin type.

  • Dry skin: morning and evening, apply SUBSTIANE [+] Serum to thoroughly cleansed skin before your day or night cream.
  • Normal to combination skin: in the morning apply under your mattifying skincare product, and use alone in the evening as a night treatment.

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